El precondicionamiento isquémico remoto mejora la cardiotoxicidad inducida por antraciclinas y mantiene la integridad mitocondrial.
Serial cardiac magnetic resonance (CMR) evaluation of a highly translatable large-animal (pig) model of anthracycline-induced cardiotoxicity (AIC) shows that cumulative exposure to anthracyclines results in significantly reduced left ventricular ejection fraction and extensive mitochondrial fragmentation. Remote Ischemic Conditioning applied before each anthracycline cycle preserved cardiac contractility and left ventricular ejection
18 junio 2021
